abm | ERBB2 and ERBB3 Stable Ba-F3 Cell Line | T6254

abm | ERBB2 and ERBB3 Stable Ba-F3 Cell Line | T6254

ERBB2 and ERBB3 Stable Ba/F3 Cell Line expresses full length ORF of ERBB2 (MSCV-puro vector) and full length ORF ERBB3 (MSCV-neo vector).
ERBB2 and ERBB3 belongs to the EGFR family of receptor tyrosine kinases consisting of proteins which bind to epidermal growth factors. Although they are important in development as they aid in the development of proper organs during embryogenesis and also maintain adult cardiac function, these proteins are best known for their role in oncogenesis. ERBB2 or Her2/neu is most known for its role in breast cancer. Both ERBB2 and ERBB3 are oncogenic targets valuable for study.

Biosafety:

II

Organism:

Mouse (M. musculus)

Source Organ:

Bone Marrow

Growth Properties:

Suspension

Morphology:

Round

Clones:

N/A

Passage Number:

N/A

Population Doner:

N/A

Seeding Density:

N/A

Markers:

ERBB2, ERBB3, puromycin and neomycin/G418 resistant

Applications:

For Research Use Only

Doner Gender:

N/A

Donor Ethnicity:

N/A

Knockdown Method:

N/A

Induction:

N/A

Overexpression:

N/A

Freeze Thaw:

N/A

Propagation:

The base medium for this cell line is Prigrow II medium available at abm

Preservation:

1. Freeze Medium: Complete growth medium with 20% FBS and 10% DMSO.
2. Storage Temperature: Liquid nitrogen vapour phase.

Quality Control:

N/A

Tumorgenicn:

N/A

Shipping Conditions:

Dry Ice

Storage Contidions:

-180°C