AffiAB® Goat Anti-HTT Polyclonal IgG Antibody

Goat Anti-Human HTT IgG Polyclonal AntibodyAB0080

Overview: Huntingtin is a protein linked to Huntington's disease, a neurodegenerative disorder characterized by loss of striatal neurons.

Other Names: HD, HTT and IT15 antibody.

Other Names: HD, HTT and IT15 antibody.

Concentration: 3 mg/ml

Antibody Type: Primary

Target Type: Anti-HTT

Accession Number: ENSG00000197386

Host Species: Goat

Immunogen Species: Human

Immunogen Type: Recombinant protein

Immunogen: Purified recombinant peptide derived from within residues 85 to 200 aa of human HTT produced in E. coli

Isotype: IgG

Clonality: Polyclonal

Confirmed Reactive Species: Human, mouse, rat, bovine, canine, chicken/avian, donkey, feline, goat, guinea pig, hamster, horse, porcine, rabbit, sheep, simian, other

Specificity Detail: Reacts huntingtin protein, amino acids 85-200. The antibody recognizes wild type and mutant huntingtin.

Buffer: PBS, 20% glycerol and 0.05% sodium azide

Purification: Epitope affinity purified

Conjugation: Unconjugated

Format: N/A

Application: WB, IF, IHC-P, IHC-F

Concentration/Dilution: WB:1:500-1:2,000, IF:1:500-1:2,000, IHC-P:1:500-1:2,000, IHC-F:1:500-1:2,000

Storage:

References: 1. Miniarikova J, Zimmer V, Martier R, et al. Gene Ther. 2017 Oct. PMID:28771234, 2. Meunier C, Merienne N, Jollé C, et al. Glia. 2016 Jul. PMID: 27442486, 3. Déglon N, Merienne N, Genome editing for the treatment of huntington's disease, EP 2982758 A1 Patent, 2014