AffiAB® Goat Anti-P53 Polyclonal IgG Antibody

AffiAB® Goat Anti-P53 Polyclonal IgG Antibody

AffiAB® Goat Anti-P53 Polyclonal IgG Antibody is a high-quality antibody designed to provide reliable detection of P53 protein. It has been validated in western blotting and immunofluorescence, offering excellent specificity and sensitivity in research applications.

Host: Goat
Species: Human

Description:

The AffiAB® Goat Anti-P53 Polyclonal IgG Antibody is an antibody designed to specifically target and detect the P53 protein. P53, also known as TP53, is a tumor suppressor protein that plays a crucial role in regulating cell cycle progression, DNA repair, and apoptosis. It is one of the most extensively studied proteins due to its involvement in various cellular processes and its association with cancer.
This polyclonal antibody is produced by immunizing goats with purified P53 protein or a specific peptide sequence derived from P53. Following immunization, the antibody is purified from goat serum to ensure high specificity and quality.

The AffiAB® Goat Anti-P53 Polyclonal IgG Antibody is widely used in research applications to investigate the expression, localization, and function of P53 in normal and diseased cells. It allows researchers to study P53's role in tumor suppression, DNA damage response, and apoptosis pathways.

By targeting P53, researchers can examine its levels and post-translational modifications in response to cellular stress, DNA damage, or oncogenic signaling. This antibody is commonly used in techniques such as Western blotting, immunohistochemistry, immunofluorescence, and immunoprecipitation, enabling the analysis of P53 expression and localization in different experimental settings.

It's important to note that the AffiAB® Goat Anti-P53 Polyclonal IgG Antibody specifically targets P53 and may not cross-react with other proteins. Researchers should validate the antibody's performance and specificity in their specific experimental conditions and ensure proper controls are included.

In summary, the AffiAB® Goat Anti-P53 Polyclonal IgG Antibody is a valuable tool for studying the P53 protein and its involvement in cellular processes, particularly in cancer research. It allows researchers to gain insights into P53's role in tumor suppression, DNA repair, and apoptosis, contributing to a better understanding of cancer biology and potential therapeutic strategies.


Gene Identifier/Accession Number: ENSG00000141510
Form: N/A
Concentration: 2.5 mg/mL
Type: Primary
Clonality: Polyclonal
Isotype: IgG
Conjugation: Unconjugated
Application: Western Blot, Immunofluorescence
Storage: For continuous use, store at 2-8 °C for one-two days. For extended storage, store in -20 °C freezer. Working dilution samples should be discarded if not used within 12 hours.
Special instructions: The antibody solution should be gently mixed before use.