AffiAB® Goat Anti-STUB1 Polyclonal IgG Antibody

The AffiAB® Goat Anti-STUB1 Polyclonal IgG Antibody is an antibody derived from goats that specifically targets and binds to STUB1, also known as CHIP (C-terminus of Hsp70-interacting protein). STUB1 is a molecular chaperone and E3 ubiquitin ligase that plays a role in protein quality control and the degradation of misfolded proteins.

The goat anti-STUB1 polyclonal antibody is produced by immunizing goats with purified STUB1 protein. The resulting antibody is then purified and used for applications such as Western blotting, immunohistochemistry, immunofluorescence, and other immunoassays.

STUB1 is involved in regulating protein homeostasis by recognizing misfolded or damaged proteins and facilitating their degradation through the ubiquitin-proteasome system. It interacts with heat shock proteins and other co-chaperones to promote the ubiquitination and subsequent degradation of target proteins.

The anti-STUB1 antibody enables the detection and specific binding of STUB1 in experimental systems, allowing researchers to investigate its function, regulation, and interaction with other proteins. By studying STUB1, researchers can gain insights into cellular processes related to protein quality control, protein folding, and degradation pathways.

When working with the AffiAB® Goat Anti-STUB1 Polyclonal IgG Antibody, it is important to follow the recommended protocols provided by the manufacturer. This includes optimizing the antibody dilution, incubation conditions, and appropriate controls for accurate and specific detection of STUB1.

Please refer to the product datasheet or manufacturer's instructions for specific guidance on the usage and recommended applications of the AffiAB® Goat Anti-STUB1 Polyclonal IgG Antibody in your research.