Carbamylated Bovine Serum Albumin (CBL-BSA) | ABMC-P28
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- ABMC-P28
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Description
Carbamylated Bovine Serum Albumin (CBL-BSA) | ABMC-P28
| Concentration: | 1 mg / ml, determined by the Lowry method |
| Source: | Bovine Serum Albumin was purchased from Boehringer Mannheim and was modified by carbamylation to form CBL modified BSA. |
| Buffer: | In 10 mM PBS, 0.15 M NaCl 0.5 mM EDTA, 0.01 % NaN3, pH 7.4. |
| Storage: | -20°C for short and long-term storage. Aliquot to avoid repeated freezing and thawing. |
*The products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
IMPORTANCE
Carbamylation is a spontaneous nonenzymatic modification of proteins and amino acids by urea-derived isocyanate, which is generally present in human serum and is increased in uremic patients (Kraus and Kraus, 2001).
Proteins carbamylated at lysine or the terminal protein amino acids may play an important role in Chronic renal failure subjects in the development of atherosclerosis and cardiovascular diseases (Raine et al., 1991; Culleton et al., 1999).
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