Candidosis RT-PCR Quant (CE) | F5-FRT

Candidosis RT-PCR Quant (CE) | F5-FRT from Sacace Biotechnologies is available for delivery

Multiplex Real Time PCR test for the quantitative detection of Candida albicans, Candida glabrata, Candida krusei, Candida parapsilosis and Candida tropicalis.

Storage & Shipping :

The kit can be shipped at 2-8°C for 3-4 days but should be stored at 2-8°C and -20°C immediately on receipt.

Candidosis RT-PCR Quant (CE) F5-FRT DataSheet

INTRODUCTION

Candida albicans is a diploid fungus that grows both as yeast and filamentous cells and a causal agent of opportunistic oral and genital infections in humans. Systemic fungal infections (fungemias) including those by C. albicans have emerged as important causes of morbidity and mortality in immunocompromised patients (e.g., AIDS, cancer chemotherapy, organ or bone marrow transplantation). In addition, hospital-acquired infections by C. albicans have become a cause of major health concerns.

Candida glabrata is a haploid yeast of the genus Candida, previously known as Torulopsis glabrata. Until recently, C. glabrata was thought to be a primarily non-pathogenic organism. However, with the ever increasing population of immunocompromised individuals, trends have shown C. glabrata to be a highly opportunistic pathogen of the urogenital tract, and of the bloodstream (Candidemia). It is especially prevalent in HIV positive people.

Candida krusei is a budding yeast (a species of fungus) involved in chocolate production. Candida krusei is an emerging fungal nosocomial pathogen primarily found in the immunocompromised and those with hematological malignancies. It has natural resistance to fluconazole, a standard antifungal agent. It is most often found in patients who have had prior fluconazole exposure, sparking debate and conflicting evidence as to whether fluconazole should be used prophylactically. Mortality due to C. krusei fungemia is much higher than the more common C. albicans.

Candida parapsilosis is a fungal species of the yeast family that has become a significant cause of sepsis and of wound and tissue infections in immuno-compromised patients. The immune system is a major player in Candida parapsilosis infections.

C. tropicalis is taxonomically close to C. albicans and shares many pathogenic traits. C. tropicalis is particularly virulent in neutropenic hosts commonly with hematogenous seeding to peripheral organs

INTENDED USE

Kit Candidosis Real-TM Quant is a multiplex Real Time PCR test for the quantitative detection of Candida albicans, Candida glabrata, Candida krusei, Candida parapsilosis and Candida tropicalis DNA in the human clinical materials.

PRINCIPLE OF ASSAY

Kit Candidosis Real-TM Quant is based on two major processes: isolation of DNA from specimens and Real Time amplification.