anti-CD8 (clone UCHT4) | 153-020

Human CD8 is a heterodimeric protein consisting of an alpha and beta chain, each about 33 kd.  CD8 is expressed on most thymocytes and on about one third of peripheral blood T cells.  CD8 is a co-receptor involved in antigen recognition and binds to the alpha 2 and alpha 3 domain of MHC Class I molecules (3, 4).

Antibodies UCHT4 and  14 (cat #154-020) each bind to a distinct epitope of CD8 and are suitable as a matched pair for EIA using UCHT4 as capture and Biotinylated clone 14(cat# 154-030) as detector.

Isotype: Murine IgG2a

Immunogen: Human thymocytes/Sezary T cells

Specificity: Antibody UCHT4 recognizes the CD8 alpha chain of approximately 33 kd (1).