FADD Polyclonal Antibody | BS-0511R

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SKU:: BS-0511R
UPC:
MPN:
Availability:: In Stock
Size:: 100ul
Concentration:: 1ug/ul
Cross Reactive Species:: Human Mouse Rat Pig Monkey
Storage:: Shipped at 4C. Store at -20C for one year.

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Description

FADD Polyclonal Antibody | BS-0511R

Host:Rabbit

Target Protein:FADD

Immunogen Range:1-80/205

Clonality:Polyclonal

Isotype:IgG

Entrez Gene:14082

Swiss Prot:Q61160

Source:KLH conjugated synthetic peptide derived from mouse FADD

Purification:Purified by Protein A.

Storage Buffer:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

Storage:Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis (By similarity). Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling (By similarity).

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