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IntroductionThe Clinical Laboratory Improvement Amendments (CLIA), passed in1988, establishes quality standards for all laboratory testing to ensure the accuracy and reliability of patient test results, regardless of where the testis performed. CLIA regulations require a laboratory to have quality control(QC) procedures to monitor the accuracy and precision of the complete testing process.This document provides a listing of QC materials that have been tested at BioFire and are compa …

Biocidal ZF™ N-86620 is Special spray-disinfectant for incubators and laminar flow hoods for protecting cultures against bacteria, fungi and enveloped viruses.Non-volatile: Active antimicrobial ingredients are non-volatile. They protect cell cultures from microbial contamination and do not invade cell cultures via air. Thus cell cultures are protected against contamination and the disinfectant itself.Active ingredients: Quaternary ammonium compounds and auxilliary components.Application: Ready-t …

Traditional process scale up using baculovirus is notoriously problematic, with yields dropping progressively during scale up. SynBac™ are minimized baculoviral genomes created using modern synthetic biology techniques. The SynBac™ project aims to transform fermenter-scale baculoviral production of drug targets, and manufacturing scale production of biopharmaceuticals by creating minimal baculoviral genomes displaying exceptional DNA stability. In addition to improved DNA stability, …

BacMam™ is an increasingly popular system that facilitates delivery of heterologous DNAs to broad range of mammalian transduction targets. BacMam uses baculovirus as a vector, and has distinct advantages over other mammalian transfection methods given the large heterologous DNA carrying capacity of baculovirus (>40kbp), the uptake of baculovirus by a broad range of mammalian cell types, and the sophisticated molecular biology technologies that have evolved over the last 20 years to support ge …

MultiBac™ expression system uses DNA recombination to allow for easy, high-throughput compatible construction of baculovirus vectors for multiprotein expression in insect cells. Multiprotein coexpression is required to produce protein complexes, such as multivalent vaccines, or multiple individual proteins in the same cell, such as for signaling pathways. Multiexpression technologies are also the cornerstone of the emerging synthetic biology revolution. The MultiBac™ platform has been used for p …