Recombinant Human Growth Hormone (rh-GH)

Human growth hormone (hGH) is a 191 amino acid non-glycosylated protein hormone secreted by the anterior pituitary gland in the brain. It is one of the most important postpartum hormones. HGH plays an important role in cell proliferation, bone formation, muscle strength, organogenesis and somatic growth as its main physiological functions are the stimulation of the rate of protein synthesis and the mobilization and utilization of fatty acids. , and the decrease in the rate of carbohydrate utilization. The Recombinant human growth hormone (rh-GH) has been approved by the US FDA as a prescription drug to treat growth disorders in children GG, severe burns, wounds, bone fractures and bone fracture; osteoporosis.

1: rh-GH Figure 1: Analysis of rh-GH by SDS-PAGE

M: protein marker standard

For research only！

Recombinant Human Growth Hormone (rh-GH) DataSheet

Biological activity: Fully biologically active compared to the standard. The ED50 as determined by a cell proliferation assay using Nb2-11 rat lymphoma cells is less than 0.1 ng / ml, corresponding to a specific activity of> 1.0 × 107 IU / mg.

Application: research, laboratory or other evaluation purposes. NOT FOR HUMAN USE.

GG stability amplifier; storage conditions:

Samples are stable for up to twelve months from date of receipt between -20 ℃ and -80 ℃
Store it in sterile conditions between -20 ℃ and -80 ℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

Advancing frontiers ：

Cyclin-dependent 4/6 kinase inhibitors in breast cancer: current status, resistance and combination strategies

Author: Niu Ying Y, Xu Junnan J

Journal: J Cancer 2019-08-29 5504-5517 22 10 DOI: 10.1002 / smll.201802403

Summary: + Deregulated activation of cyclin-dependent kinases (CDK) 4/6, leading to uncontrolled cell division, is characteristic of cancers.

Molecular and computational analysis of ghrelin, growth hormone secretagogues receptor and mRNA expression of growth-related genes after exogenous administration of ghrelin peptide in Labeo rohita

Author: Dar Showkat Ahmad SA, Srivastava Prem P PP, Rather Mohd Ashraf MA, Varghese Tincy T, Rasool Sheikh Irfan SI

Journal: Int. J. Biol. Macromol. 2019-10-14 DOI: 10.1002 / smll.201802403 Summary: + Ghrelin is a peptide hormone secreted primarily by the stomach and is involved in the control of growth by governing various functions in vertebrates, including food intake and metabolism in vertebrates.

Association between FGFR1 copy number, MAP3K1 mutations and survival in early breast cancers with axillary node positive, hormone receptor positive and HER2 negative in PACS04 and METABRIC studies

Author: Carene Dimitri D, Tran-Dien Alicia A, Lemonnier Jérôme J, Dalenc Florence F, Levy Christelle C, Pierga Jean-Yves JY, Jacot William W, Canon Jean-Luc JL, Richon Catherine C

Journal: Breast Cancer Res. To treat. 10/16/2019 DOI: 10.1002 / smll.201802403

Summary: Human epidermal growth factor (HER2-) receptor 2 negative hormone receptor positive (HR {2}}) early breast cancer (BC) is the most common BC subtype with substantial biological heterogeneity.