Spike Variant

A new emerging variant of SARS-CoV-2, named CAL.20C or lineage B.1.429, was recently reported in California (US). Identified by researchers at Cedars-Sinai Medical Center in July 2020, the variant was initially reported as rare only to resurface later...

The accumulation of mutations K417N, E484K and N501Y in the receptor-binding domain (RBD) of the spike in the new coronavirus, SARS-CoV-2, has been recently described in an emerging variant of the virus. The variant, commonly known as the South African...

SARS-CoV-2 is an enveloped positive-sense single-stranded RNA virus from the Coronavirus family. First identified in the Wuhan province (China) in December 2019 as the etiological agent of the COVID-19 disease, SARS-CoV-2 was soon classified as a...

A new emerging variant of SARS-CoV-2 was detected in December 2020 in Manaus (Amazonas state, Brazil). The variant belongs to a new lineage of the virus – lineage P.1, which, according to genomic analysis, descends from an earlier Brazilian variant...

The N501Y mutation in the receptor-binding domain (RBD) has been detected in an emerging variant of SARS-CoV-2. The variant, known as the B.1.1.7 lineage, Variant of Concern (VOC) 202012/01, or clade 20B/501Y.V1, was first discovered in Kent, United...

The spike glycoprotein is the most important antigen in the pandemic strain of coronavirus, SARS-CoV-2, the causative agent of the COVID-19 respiratory disease. Containing a complex transmembrane domain and exposed on a trimeric form on the surface of...