Goat Anti-Human Apolipoprotein CIII Sepharose 4B™ Gel | ABMC-G04
- SKU:
- ABMC-G04
- Availability:
- Usually shipped in 5 working days
Description
Goat Anti-Human Apolipoprotein CIII Sepharose 4B™ Gel | ABMC-G04
| Host Species: | Goat |
| Concentration: | ≥ 5 mg/ml |
| Source: |
Polyclonal goat antibody human apo CIII coupled with CNBr-activated Sepharose 4B™. |
| Preservation: |
75 mM PBS, 75 mM NaCl, 0.5 mM EDTA, 0.02% NaN3, 0.1mM PMSF, pH 7.3. |
| Specificity |
Specifically binds to human apo CIII. |
| Use: |
Affinity purification column. |
| Storage: |
2-8ºC store in buffer with 0.5 mM EDTA and 0.02% NaN3, 0.1 mM PMSF. DO NOT FREEZE! |
*Sepharose is a trademark of GE Healthcare Life Sciences, Sweden.
** These products are for research or manufacturing use only, not for use in human therapeutic or diagnostic applications.
IMPORTANCE
Apo CIII contains 79 amino acid residues. The m.w. is 8.7 kDa (Brewer et al., 1974).
It may inhibit the activation of lipoprotein lipase by apo CIII. Apo CIII is a constituent of both apoB- and apoAI-containing lipoproteins in the circulation. Apo CIII plays a pivotal role in regulating the plasma metabolism of VLDL, IDL, and LDL, primarily by inhibiting receptor-mediated uptake of these lipoproteins by the liver (Sehayek and Eisenberg 1991, Aalto-Setala et al., 1992, Zheng et al., 2007)
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