Quality Controls for M. tuberculosis Testing

INTROL® TB Panel M110

Drug Resistance Mutations found in INTROL TB Panel M110:

Catalog No: M110
4 bottles x 3 mL
1 bottle each:
TBWT-04, TBMDR1-04, TBMDR2-04 & TBNEG
Control             Drug Resistance Mutation
INTROL® TBWT-04 Wild type
rpoB: F505L, L511P, D516V, H526Y
INTROL® TBMDR1-04 inhA: -15
katG: S315T (AGC> ACC)
rpoB: S522L, H526D, S531L
INTROL® TBMDR2-04 inhA: -8
katG: S315T (AGC>ACA)
INTROL® TBNEG No MTB DNA, no cells

INTROL® TB Panel M114 (for the GeneXpert®)

Drug Resistance Mutations found in INTROL TB Panel M114:

Catalog No’s:
M114-5: 15 bottles x 1.0 mL
5 bottles each:
TBWT-04, TBMDR1-04 & TBNEG
M114-10: 30 bottles x 1.0 mL
10 bottles each:
TBWT-04, TBMDR1-04 & TBNEG
Control             Mutation
INTROL® TBWT-04 Wild type
rpoB: F505L, L511P, D516V, H526Y
INTROL® TBMDR1-04 inhA: -15
katG: S315T (AGC> ACC)
INTROL® TBNEG No MTB DNA, no cells

INTROL® TB Panel M114plus (for the GeneXpert®)

**Now all drug resistance mutations in 1 panel. Plus IS1081**

Drug Resistance Mutations found in INTROL TB Panel M114plus:

Catalog No: M114plus
12 bottles x 1.0 mL
3 bottles each:
TBWT-04, TBMDR1-04, TB1081MDR2 & TBNEG
Control              Drug Resistance Mutation
INTROL® TBWT-04 Wild type
rpoB: F505L, L511P, D516V, H526Y
INTROL® TBMDR1-04 inhA: -15
katG: S315T (AGC> ACC)
INTROL® TB1081MDR2 rpoB: S522L, H526D, S531L
inhA: -8T>C
INTROL® TBNEG No MTB DNA, no cells

INTROL® TBNEG-30 (for the GeneXpert®)

Catalog No: M115
30 bottles of TBNEG x 1.0 mL
Control          Mutation
INTROL® TBNEG No MTB DNA, no cells

INTROL® TB-XDR Panel M345 (for the GeneXpert®)

Drug Resistance Mutations found in INTROL TB-XDR Panel M345

Catalog No: M345-5
15 bottles x 1.0 mL
5 bottles each:
TB-XDR WT, TB-XDR MUT & TB-XDR NEG
Control               Mutation
INTROL® TB-XDR WT Wild type
eis promoter (-14 C>T), fabG1: L203L (CTg>CTa),
INTROL® TB-XDR MUT gyrA: D94G (GaC > GgC), gyrB: E540D (GAa >GAc)
inhA promoter: (-15 C>T), katG: S315T (AgC > AcC),
oxyR-ahpC (-39 C>T) and rrs (a1401g)
INTROL® TB-XDR NEG No MTB DNA, no cells

13th Jun 2021

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