Quality Controls for M. tuberculosis Testing
Drug Resistance Mutations found in INTROL TB Panel M110:
| Catalog No: M110 |
| 4 bottles x 3 mL |
| 1 bottle each: |
| TBWT-04, TBMDR1-04, TBMDR2-04 & TBNEG |
| Control | Drug Resistance Mutation | |
| INTROL® TBWT-04 | Wild type | |
| rpoB: F505L, L511P, D516V, H526Y | ||
| INTROL® TBMDR1-04 | inhA: -15 | |
| katG: S315T (AGC> ACC) | ||
| rpoB: S522L, H526D, S531L | ||
| INTROL® TBMDR2-04 | inhA: -8 | |
| katG: S315T (AGC>ACA) | ||
| INTROL® TBNEG | No MTB DNA, no cells |
INTROL® TB Panel M114 (for the GeneXpert®)
Drug Resistance Mutations found in INTROL TB Panel M114:
| Catalog No’s: |
| M114-5: 15 bottles x 1.0 mL |
| 5 bottles each: |
| TBWT-04, TBMDR1-04 & TBNEG |
| M114-10: 30 bottles x 1.0 mL |
| 10 bottles each: |
| TBWT-04, TBMDR1-04 & TBNEG |
| Control | Mutation | |
| INTROL® TBWT-04 | Wild type | |
| rpoB: F505L, L511P, D516V, H526Y | ||
| INTROL® TBMDR1-04 | inhA: -15 | |
| katG: S315T (AGC> ACC) | ||
| INTROL® TBNEG | No MTB DNA, no cells |
INTROL® TB Panel M114plus (for the GeneXpert®)
**Now all drug resistance mutations in 1 panel. Plus IS1081**
Drug Resistance Mutations found in INTROL TB Panel M114plus:
| Catalog No: M114plus |
| 12 bottles x 1.0 mL |
| 3 bottles each: |
| TBWT-04, TBMDR1-04, TB1081MDR2 & TBNEG |
| Control | Drug Resistance Mutation | |
| INTROL® TBWT-04 | Wild type | |
| rpoB: F505L, L511P, D516V, H526Y | ||
| INTROL® TBMDR1-04 | inhA: -15 | |
| katG: S315T (AGC> ACC) | ||
| INTROL® TB1081MDR2 | rpoB: S522L, H526D, S531L | |
| inhA: -8T>C | ||
| INTROL® TBNEG | No MTB DNA, no cells |
INTROL® TBNEG-30 (for the GeneXpert®)
| Catalog No: M115 |
| 30 bottles of TBNEG x 1.0 mL |
| Control | Mutation | |
| INTROL® TBNEG | No MTB DNA, no cells |
INTROL® TB-XDR Panel M345 (for the GeneXpert®)
Drug Resistance Mutations found in INTROL TB-XDR Panel M345
| Catalog No: M345-5 |
| 15 bottles x 1.0 mL |
| 5 bottles each: |
| TB-XDR WT, TB-XDR MUT & TB-XDR NEG |
| Control | Mutation | |
| INTROL® TB-XDR WT | Wild type | |
| eis promoter (-14 C>T), fabG1: L203L (CTg>CTa), | ||
| INTROL® TB-XDR MUT | gyrA: D94G (GaC > GgC), gyrB: E540D (GAa >GAc) | |
| inhA promoter: (-15 C>T), katG: S315T (AgC > AcC), | ||
| oxyR-ahpC (-39 C>T) and rrs (a1401g) | ||
| INTROL® TB-XDR NEG | No MTB DNA, no cells |
13th Jun 2021
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